Study on the effect of hyoscine-N-butylbromide suppository on pain and process of Labor

Labor is a painful process and one of the midwives duties is trying to reduce the intensity of labor pain, in which reduction of duration of clinical stages of labor has always been considered. The objective of this study was to evaluate the effect of hyoscine suppository on labor pain and process of labor. This double-blind clinical trial was down on 130 nulliparous pregnant women who referred to Ahvaz Sina hospital for parturition. A hyoscine suppository was given to case group and a placebo suppository was given to control group at beginning of active phase of labor, rectally. Then the labor pain mean, cervical dilatation and effacement progress, active phase and second stage duration and delivery type were recorded. The data were analyzed using T, Chi square and Fisher tests in 0.05 significant level in SPSS Version 15.0. were significant differences between mean of cervical dilatation and effacement 1 and 2 h after intervention in both groups [P<0.0001]. The active phase and second stage duration in case group were less than control group significantly [P=0.007]. Caesarean section rate in the case group was less than control group, but the difference was not significant [P=:0.07]. Labor pain intensity had not significant difference in both groups. There were no differences in fetal heart rate, maternal pulse rate and blood pressure and neonatal APGAR score between both groups. It seems that hyoscine suppository can be used to accelerate the process of labor and reduce duration of labor pain, effectively, but does not reduce labor pain

[Cutaneous metastasis of choriocarcinoma]

Cutaneous metastasis is a rare presentation of choriocarcinoma and as it is associated with advanced disease, it has poor prognostic sign. To the best of our knowledge about 11 cases of cutaneous metastatic choriocarcinoma were reported in the literature. A 47-yr -old female complaining of cutaneous lesion with pruritis. She had history of choriocarcinoma following missed abortion. Skin biopsy revealed cytotrophoblast and syncitotrophoblast without chorionic villi. After 3 cycles of chemotherapy, serum betaHCG decreased and skin lesion almost disappeared. As compared to other organs, skin is an uncommon site for metastatic cancer in the body, as it is usually associated with disseminated disease and grave outcome. However, cutaneous metastasis may be the first harbinger of visceral malignancy of unknown origin and could be an important diagnostic clue. Gynecologists should consider meticulously skin lesions in known cases of disease and even in patients without history of disease, because skin lesion may be the first sign of the disease

[Prevalence of gestational trophoblastic disease and relative factors]

Gestational trophoblastic disease [GTD] is one of the rare neoplastic diseases that remains curable even with a lot of metastases, but if left untreated, it can be life threatening. We had an increase in number of GTD during recent years in Ahvaz. The aim of this study was to determine the prevalence and risk factors of trophoblastic diseases among women who were admitted in Imam Khomaini Hospital, Ahvaz, Iran. In this cross-sectional study, all hospital records related to trophoblastic diseases [n=132] were reviewed from 1996 up to 2006. Demographic and histo-pathologic data were taken using a questionnaire containing 34 questions. The Chi-square, "t" and Exact -Fisher tests were used to analyze all data. P

[ effect of massage with coconut oil on weight gain in preterm neonate]

One of the most common and important problems in neonates is low birth weight [LBW]. The prevalence of LBW in Iran is estimated 12%, 30-50% of whom are preterm. Improvement in care procedures of these neonates in addition to decrease the cost of care can cause reduction in complications of neonatal, childhood and adulthood period. With regarding to the importance of growth and development, this study was conducted to evaluate the effect of massage with coconut oil on weight gain of preterm neonates. This study is a clinical trial which was carried out on 72 healthy preterm neonates with gestational age between 34-37 weeks who had the conditions of entrance to the study. The sampling was done randomly based on purpose of the study. Neonates were divided into three equal groups [24 in each]: control, massage and massage with oil. In massage group: massaging were done 3 times-a-day and each session lasted for 5 minutes based on the teacher techniques started from the days 3 to 17 after birth by the mother. In the oil-massage group the same techniques were done with 10 ml/kg coconut oil for the same period. In control group there were no interventions. Weights were measured, 7[th] and 14[th] days after birth. The average gestational age at birth was 35-37 weeks. The average weight was 2314 g and there was no significant difference between these groups. There was a significant difference in average weight gain 7 days after intervention in massage with oil[2525.42 gr] to control group [2267.29 gr] [P=0.04] and in massage [2444.38 gr] to control group [P=0.02]. On day 14 after intervention there was a significant difference in massage with oil [2789.58 gr] to control group [2375.42 gr] [P< 0.001] and in massage [2606.67 gr] to control group [P< 0.01] and also there was a significant difference between massage with oil to massage group [P=0.04]. This study showed that massage and especially massage with oil is an effective and valuable method in weight gain in preterm neonates

[ comparison of the acupressure and pyridoxine effect on severity of both nausea and vomiting in primigravida women]

Gastric disorders especially nausea and vomiting are the most common complaint during pregnancy. Previous studies have shown that nearly 20% of pregnant women visited physician for these problems. The aim of this study was to compare the effect of acupressure and Vit. B6 [pyridoxine] on reduction of nausea and vomiting in primigravida women. In a clinical trial study, 100 women with gestational age of 10-16 weeks and single fetus were randomly selected from primigravida women who referred to antenatal care centers of Ahvaz for nausea and vomiting. Then they were allocated to acupressure [n=50] or pyridoxine group [n=50]. Treatment with acupressure or pyridoxine was carried out for four days. In acupressure group sea band was placed on the neiguan [p6] point of hand and in pyridoxine group, each patient had 40 mg of Vit. B6 every day. Severity of nausea and vomiting was recorded by each subjects. Data was analyzed by Chi-square, Manwithney, Wilcoxon and t-tests. Our results showed that nausea score and frequency of vomiting were decreased significantly by both treatments [p<0.001]. Also acupressure was significantly more effective in reduction of vomiting frequency [p<0.001]. The severity of nausea was not different in two groups. Our results showed that acupressure was more effective than Vitamin. B6 in treatment of pregnancy vomiting. Regarding the fact that sea band is cheap, comfortable, available and easily use, it is recommended to reduce vomiting in pregnancy